Directory

Karen J. Haman

  • Lecturer
  • Chemical and Biological Engineering

Main Office

1037 Sweeney
Ames, IA 50011-1098
Phone: 515-294-7195




Education

  • B.S.E., Chemical Engineering, University of Iowa, 2009
  • Ph.D., Chemical Engineering, University of Minnesota, 2015

Interest Areas

Research Interests

  • Amphiphilic block copolymer synthesis and interaction with model cell membranes
  • Thesis: Development of Diblock Copolymer Surfactants for Mechanistic Investigations of Cell Membrane Stabilization

 Teaching Fall Semester 2017

  • Ch E 358, Separations (Section B)
  • Ch E 426, Ch E Lab II (Section A)
  • ChE 391, Study Abroad Prep -- Oviedo, Spain
   

Selected Publications

  • Houang, E. M.; Haman, K. J.; Kim, M.; Zhang, W.; Lowe, D. A.; Sham, Y. Y.; Lodge, T. P.; Hackel, B. J.; Bates, F. S.; Metzger, J. M. Chemical End Group Modified Diblock Copolymers Elucidate Anchor and Chain Mechanism of Membrane Stabilization. Mol. Pharm. 2017, 14 (7), 2333–2339.
  • Kim, M.; Haman, K. J.; Houang, E. M.; Zhang, W.; Yannopoulos, D.; Metzger, J. M.; Bates, F. S.; Hackel, B. J. PEO–PPO Diblock Copolymers Protect Myoblasts from Hypo-Osmotic Stress In Vitro Dependent on Copolymer Size, Composition, and Architecture. Biomacromolecules 2017, 18 (7), 2090–2101.
  • Zhang, W.; Haman, K. J.; Metzger, J. M.; Hackel, B. J.; Bates, F. S.; Lodge, T. P. Quantifying Binding of Ethylene Oxide–Propylene Oxide Block Copolymers with Lipid Bilayers. Langmuir 2017, 33 (44), 12624–12634.
  • Houang, E. M.; Haman, K. J.; Filareto, A.; Perlingeiro, R. C.; Bates, F. S.; Lowe, D. A.; Metzger, J. M. "Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo." Mol. Ther. - Methods Clin. Dev. 2015, 2 (15042). http://www.fasebj.org/content/29/1_Supplement/1039.3.short
  • Bartos, J. A.; Matsuura, T. R.; Tsangaris, A.; Olson, M.; McKnite, S. H.; Rees, J. N.; Haman, K.; Shekar, K. C.; Riess, M. L.; Bates, F. S.; et al. Intracoronary Poloxamer 188 Prevents Reperfusion Injury in a Porcine Model of ST-Segment Elevation Myocardial Infarction. JACC Basic to Transl. Sci. 2016, 27. http://dx.doi.org/10.1016/j.jacbts.2016.04.001